Peptide Education at The Root Connection™

Semaglutide is a prescription medication that belongs to a class called GLP-1 receptor agonists. It was originally developed to help manage blood sugar levels in people with type 2 diabetes and is now also used by medical providers to support weight management in certain individuals.

GLP-1 is a hormone your body naturally produces that plays a role in appetite, digestion, and blood sugar regulation. Semaglutide is designed to mimic this natural hormone.

Semaglutide works by supporting communication between the gut and the brain. It helps:

• Slow how quickly food leaves the stomach
   
• Increase feelings of fullness after eating
   
• Reduce appetite and food noise
   
• Support more stable blood sugar patterns
   

By reinforcing natural satiety signals, GLP-1 therapy can make it easier for some people to eat less without feeling deprived, especially when paired with nutrition and lifestyle support.

Under licensed medical supervision, GLP-1 therapy may be considered for adults who:

• Struggle with weight despite lifestyle efforts
   
• Experience strong appetite or cravings
   
• Have insulin resistance or metabolic imbalance
   
• Are looking for medical support alongside nutrition and behavior changes
   

Eligibility is determined by a medical provider based on health history, labs, and individual risk factors.

GLP-1 therapies are not appropriate for everyone. They may not be recommended for individuals with:

• A personal or family history of medullary thyroid cancer
   
• Multiple endocrine neoplasia syndrome type 2 (MEN2)
   
• Certain gastrointestinal conditions
   
• A history of severe reactions to GLP-1 medications
   

Common side effects can include nausea, digestive discomfort, or changes in appetite, especially during the early stages of use. Ongoing medical monitoring is important.

Tirzepatide is a prescription medication used under medical supervision to support blood sugar regulation and weight management in certain individuals. It belongs to a newer class of medications that work on two metabolic hormones, GLP-1 and GIP.

Both GLP-1 and GIP are hormones your body naturally releases after eating and are involved in appetite regulation, digestion, and blood sugar control. Tirzepatide is designed to act on both pathways.

Tirzepatide supports metabolic signaling in a few key ways:

• Enhances feelings of fullness after meals
   
• Helps reduce appetite and food noise
   
• Slows digestion so you feel satisfied longer
   
• Supports more stable blood sugar patterns
   

By influencing both GLP-1 and GIP pathways, tirzepatide may provide broader metabolic support for some individuals compared to GLP-1 therapy alone. Nutrition, movement, and lifestyle habits remain essential parts of any treatment plan.

Under licensed medical supervision, tirzepatide may be considered for adults who:

• Have insulin resistance or metabolic dysfunction
   
• Have struggled with weight despite lifestyle changes
   
• Have type 2 diabetes or impaired glucose regulation
   
• May not have responded optimally to GLP-1 therapy alone
   

A medical provider determines eligibility based on medical history, labs, and individual risk factors.

Tirzepatide is not appropriate for everyone. It may not be recommended for individuals with:

• A personal or family history of medullary thyroid cancer
   
• Multiple endocrine neoplasia syndrome type 2 (MEN2)
   
• Certain gastrointestinal conditions
   
• A history of severe reactions to similar medications
   

Side effects may include nausea, digestive discomfort, fatigue, or appetite changes, particularly during early dose adjustments. Ongoing provider monitoring is important to ensure safety and tolerance.

Sermorelin is a prescription medication used under medical supervision to support the body’s natural production of growth hormone. Rather than supplying growth hormone directly, sermorelin works by signaling the pituitary gland to release more of the growth hormone your body already makes.

Growth hormone plays an important role in metabolism, muscle repair, sleep quality, energy levels, and overall recovery as we age.

Sermorelin mimics a naturally occurring hormone in the body that stimulates growth hormone release. By encouraging this natural process, it may help support:

• Improved sleep quality
   
• Muscle recovery and strength
   
• Fat metabolism
   
• Energy and vitality
   
• Overall tissue repair
   

Because it works with the body’s existing systems, sermorelin is often described as a gentler, more physiologic approach compared to direct growth hormone therapy.

Under licensed medical supervision, sermorelin may be considered for adults who:

• Experience low energy or poor recovery
   
• Notice changes in body composition with age
   
• Have disrupted sleep patterns
   
• Want to support healthy aging and metabolic function
   
• Have confirmed low or declining growth hormone levels
   

A medical provider determines whether sermorelin is appropriate based on symptoms, health history, and diagnostic evaluation.

Sermorelin is not appropriate for everyone. It may not be recommended for individuals with:

• Active or recent cancer
   
• Certain pituitary disorders
   
• Known hypersensitivity to sermorelin
   
• Pregnancy or breastfeeding
   

Possible side effects may include injection site irritation, headache, flushing, or mild dizziness. Medical supervision and follow-up are essential to ensure safety.

Glutathione is a powerful antioxidant that your body naturally produces. It plays a critical role in protecting cells from damage, supporting the immune system, and assisting the body’s natural detox processes.

In clinical settings, glutathione may be used under medical supervision to support individuals who have increased oxidative stress, toxin exposure, chronic illness, or reduced detox capacity.

Glutathione works inside cells to help neutralize free radicals and support the body’s natural ability to process and remove waste. It is especially active in the liver, where many detox and filtering processes occur.

Glutathione helps:

• Protect cells from oxidative damage
   
• Support liver detox pathways
   
• Assist immune system function
   
• Reduce overall inflammatory stress
   
• Support recovery during periods of high physical or environmental load
   

Because glutathione levels can decline with age, illness, stress, or toxin exposure, some individuals may benefit from medical support to restore adequate levels.

Under licensed medical supervision, glutathione support may be considered for individuals who:

• Experience chronic fatigue or inflammation
   
• Have high toxic or environmental exposure
   
• Are undergoing metabolic or wellness therapies
   
• Want to support liver and immune function
   
• Have difficulty tolerating traditional detox approaches
   

A healthcare provider determines the appropriate use based on health history, symptoms, and individual needs.

Glutathione is not appropriate for everyone. Caution may be needed for individuals with:

• Certain asthma conditions
   
• Sulfur sensitivities
   
• Active chemotherapy or specific medical treatments
   
• Known reactions to glutathione or related compounds
   

Side effects are generally mild but may include headache, nausea, or digestive discomfort. Medical guidance is important to determine the appropriate form and use.

GHK-Cu, often called a copper peptide, is a naturally occurring compound found in the human body. It plays an important role in tissue repair, skin health, inflammation regulation, and cellular signaling. Levels of GHK-Cu naturally decline with age.

In clinical and functional medicine settings, GHK-Cu may be used under medical supervision to support repair and regeneration at the cellular level.

GHK-Cu works by sending signals to cells involved in repair and renewal. It helps activate processes related to:

• Tissue repair and wound healing
   
• Collagen and elastin production
   
• Skin integrity and firmness
   
• Inflammation modulation
   
• Cellular communication and recovery
   

Rather than forcing a response, GHK-Cu supports the body’s natural repair mechanisms, making it of interest in both aesthetic and recovery-focused care.

Under licensed medical supervision, GHK-Cu may be considered for individuals who:

• Notice skin changes related to aging
   
• Are recovering from injury or tissue stress
   
• Want to support collagen and connective tissue health
   
• Experience chronic inflammation or delayed healing
   
• Are interested in regenerative or restorative therapies
   

A medical provider determines appropriateness based on health history, goals, and individual risk factors.

GHK-Cu is not appropriate for everyone. Caution may be advised for individuals with:

• Copper metabolism disorders
   
• Wilson’s disease
   
• Known sensitivity to copper-containing compounds
   
• Certain chronic liver conditions
   

Possible side effects are generally mild but may include skin irritation or sensitivity, depending on the form used. Medical supervision helps ensure safe and appropriate use.

NAD⁺ (nicotinamide adenine dinucleotide) is a molecule naturally found in every cell of the body. It plays a critical role in cellular energy production, DNA repair, and nervous system function. NAD⁺ levels naturally decline with age, stress, illness, and metabolic strain.

In functional and integrative medical settings, NAD⁺ may be used under licensed provider supervision to support cellular health, cognitive function, and overall resilience.

NAD⁺ helps cells convert nutrients into usable energy and supports processes involved in repair and recovery. It is especially important for:

• Mitochondrial (cellular energy) function
   
• Brain and nervous system signaling
   
• Cellular repair and longevity pathways
   
• Recovery from metabolic or neurologic stress
   

Supporting NAD⁺ levels may help improve how efficiently cells respond to physical, mental, and environmental demands.

NAD⁺ can be delivered in different forms, each with distinct considerations. A licensed medical provider determines the most appropriate option.

• Delivers NAD⁺ directly into the body for systemic absorption
   
• Often used when higher or more consistent blood levels are desired
   
• May be considered for individuals with significant fatigue, cognitive stress, or recovery needs
   
• Requires injections and medical oversight
   

Injection delivery is typically chosen when deeper, whole-body cellular support is the goal.

• Absorbed through the nasal passages, with potential direct access to the brain
   
• Often used for cognitive support, mental clarity, or nervous system balance
   
• Non-invasive and easier to administer
   
• May provide more localized or gentle support compared to injections
   

Nasal delivery is often selected for individuals seeking brain-focused support or a less invasive option.

Under licensed medical supervision, NAD⁺ support may be considered for individuals who:

• Experience chronic fatigue or low energy
   
• Notice cognitive fog or reduced mental clarity
   
• Are under high physical or mental stress
   
• Want to support healthy aging and cellular function
   
• Are recovering from illness or prolonged metabolic strain
   

Appropriateness and delivery method are determined by a medical provider based on individual needs and health history.

NAD⁺ support is not appropriate for everyone. Caution may be needed for individuals with:

• Certain neurological conditions
   
• Sensitivity to rapid metabolic shifts
   
• Active cancer or specific medical treatments
   

Possible side effects may include flushing, nausea, headache, or temporary discomfort, depending on the delivery method. Medical supervision helps ensure safe and appropriate use.